Oropharyngeal cancer affects the middle of the throat, including the tonsils and the base of the tongue. A growing number of these cancers are linked to HPV, and they often show up first as a lump in the neck or a sore throat that does not settle. Modern treatment, including robotic surgery through the mouth, gives good results with fewer side effects. At THANC Hospital in Chennai, Dr. Vidhyadharan Sivakumar treats oropharyngeal cancer with TORS, radiotherapy and multidisciplinary care. This page is part of our wider head and neck cancer care.
Understanding Oropharyngeal Cancer
The oropharynx is the middle part of the throat. It includes the tonsils, the base of the tongue, the soft palate and the back wall of the throat. Cancer here is usually a squamous cell carcinoma. There are two main groups: cancers linked to HPV infection, and cancers linked to tobacco and alcohol.
HPV-related cancers are becoming more common. They often affect slightly younger, non-smoking patients and usually respond very well to treatment, with a better outlook. You can read more in our guide on HPV and oropharyngeal cancer.
Symptoms
See a specialist if you notice:
- A sore throat that does not settle
- Difficulty or pain when swallowing
- A lump in the neck, often the first sign of an HPV-related cancer
- Ear pain on one side, with a normal ear
- A change in voice or a feeling of something stuck in the throat
Our guide on throat cancer symptoms covers the warning signs in detail.
Diagnosis at THANC Hospital
Dr. Vidhyadharan uses a clear pathway:
- Flexible scope examination of the throat.
- Biopsy to confirm the cancer, with HPV testing.
- CT, MRI or PET-CT to stage the cancer and check the neck.
- Multidisciplinary tumour board review to agree the plan.
Why HPV Status Matters
Whether an oropharyngeal cancer is caused by HPV makes a real difference to treatment and outlook. HPV-related cancers usually respond very well to treatment and have a better outcome, even when they have spread to the neck nodes. Because of this, the team works to keep treatment as gentle as possible while still curing the cancer. Tobacco-related cancers behave differently and may need fuller treatment. This is why every biopsy is tested for HPV, and why the test shapes the plan that follows. Our guide explains more about HPV and oropharyngeal cancer.
How It Is Treated
The aim is to cure the cancer while protecting swallowing and speech as much as possible. The plan depends on the stage and the HPV status.
Transoral Robotic Surgery (TORS)
For many tonsil and tongue-base cancers, TORS removes the tumour through the mouth using the da Vinci robot, with no external cuts on the neck or jaw. The magnified, precise view helps remove the cancer cleanly while protecting the muscles and nerves used for swallowing and speech. For early cancers, TORS can sometimes be the only treatment needed, or it can reduce the dose of radiotherapy that follows. Learn more on our TORS robotic throat cancer surgery page and in our guide on robotic surgery explained.
Radiotherapy and Chemoradiation
Radiotherapy, sometimes combined with chemotherapy, is a key treatment for oropharyngeal cancer. It may be used on its own for some cancers, or after surgery for higher-risk ones. Modern radiotherapy is targeted to reduce damage to healthy tissue, but it still affects the mouth and throat during treatment, so support during this time is important.
Neck Treatment
Because these cancers often spread to the neck nodes, the neck is usually treated as well, either with a neck dissection or with radiotherapy. The tonsil is one of the most common sites within the oropharynx, covered on our tonsil cancer page.
What to Expect
Before treatment. A scope examination, a biopsy with HPV testing, staging scans and a tumour board review. Dr. Vidhyadharan explains the diagnosis, the plan and the likely recovery.
Treatment. TORS, radiotherapy or a combination, with neck treatment as needed.
After treatment. Follow-up checks the throat and neck, with support for swallowing and speech during recovery.
Outcomes
The outlook for oropharyngeal cancer is generally good, and especially good for HPV-related cancers caught early, many of which are cured. Stage at diagnosis and complete treatment are the main factors. Function-sparing approaches like TORS help patients keep good swallowing and speech, so quality of life after treatment is usually high. A sore throat or neck lump that does not settle should be checked early, because the earlier the cancer is found, the gentler the treatment can be.
Why Choose Dr. Vidhyadharan at THANC Hospital
- India's first TORS-assisted total laryngectomy (2022), a landmark in robotic head and neck surgery.
- FICRS certification in robotic surgery, with fellowship training at Royal Adelaide Hospital, Australia.
- MCh (Head & Neck Surgery) and European Board certification (FEB-ORL HNS).
- 3000+ head and neck operations, the volume linked to better outcomes.
- The da Vinci Xi robot and a full oncology team at THANC Hospital.
Treatment Cost and Insurance
The cost depends on the stage, the treatment (surgery, radiotherapy or both), and the length of stay. Most major health insurers in India cover cancer treatment, including cashless treatment at empanelled hospitals. Eligible patients may also use government schemes such as Ayushman Bharat (AB-PMJAY) or the Tamil Nadu CMCHIS.
THANC Hospital gives a clear, itemised estimate during your consultation. To see Dr. Vidhyadharan Sivakumar, request an appointment online.




