Oropharyngeal Cancer Treatment - Dr. Vidhyadharan Sivakumar
Head & Neck Cancer

Oropharyngeal Cancer Treatment

Dr. Vidhyadharan Sivakumar|MCh (Head & Neck Surgery) · FEB-ORL HNS · FICRS
5 min readLast reviewed: June 2026

Oropharyngeal cancer affects the middle of the throat, including the tonsils and the base of the tongue. A growing number of these cancers are linked to HPV, and they often show up first as a lump in the neck or a sore throat that does not settle. Modern treatment, including robotic surgery through the mouth, gives good results with fewer side effects. At THANC Hospital in Chennai, Dr. Vidhyadharan Sivakumar treats oropharyngeal cancer with TORS, radiotherapy and multidisciplinary care. This page is part of our wider head and neck cancer care.

Understanding Oropharyngeal Cancer

The oropharynx is the middle part of the throat. It includes the tonsils, the base of the tongue, the soft palate and the back wall of the throat. Cancer here is usually a squamous cell carcinoma. There are two main groups: cancers linked to HPV infection, and cancers linked to tobacco and alcohol.

HPV-related cancers are becoming more common. They often affect slightly younger, non-smoking patients and usually respond very well to treatment, with a better outlook. You can read more in our guide on HPV and oropharyngeal cancer.

Symptoms

See a specialist if you notice:

  • A sore throat that does not settle
  • Difficulty or pain when swallowing
  • A lump in the neck, often the first sign of an HPV-related cancer
  • Ear pain on one side, with a normal ear
  • A change in voice or a feeling of something stuck in the throat

Our guide on throat cancer symptoms covers the warning signs in detail.

Diagnosis at THANC Hospital

Dr. Vidhyadharan uses a clear pathway:

  • Flexible scope examination of the throat.
  • Biopsy to confirm the cancer, with HPV testing.
  • CT, MRI or PET-CT to stage the cancer and check the neck.
  • Multidisciplinary tumour board review to agree the plan.

Why HPV Status Matters

Whether an oropharyngeal cancer is caused by HPV makes a real difference to treatment and outlook. HPV-related cancers usually respond very well to treatment and have a better outcome, even when they have spread to the neck nodes. Because of this, the team works to keep treatment as gentle as possible while still curing the cancer. Tobacco-related cancers behave differently and may need fuller treatment. This is why every biopsy is tested for HPV, and why the test shapes the plan that follows. Our guide explains more about HPV and oropharyngeal cancer.

How It Is Treated

The aim is to cure the cancer while protecting swallowing and speech as much as possible. The plan depends on the stage and the HPV status.

Transoral Robotic Surgery (TORS)

For many tonsil and tongue-base cancers, TORS removes the tumour through the mouth using the da Vinci robot, with no external cuts on the neck or jaw. The magnified, precise view helps remove the cancer cleanly while protecting the muscles and nerves used for swallowing and speech. For early cancers, TORS can sometimes be the only treatment needed, or it can reduce the dose of radiotherapy that follows. Learn more on our TORS robotic throat cancer surgery page and in our guide on robotic surgery explained.

Radiotherapy and Chemoradiation

Radiotherapy, sometimes combined with chemotherapy, is a key treatment for oropharyngeal cancer. It may be used on its own for some cancers, or after surgery for higher-risk ones. Modern radiotherapy is targeted to reduce damage to healthy tissue, but it still affects the mouth and throat during treatment, so support during this time is important.

Neck Treatment

Because these cancers often spread to the neck nodes, the neck is usually treated as well, either with a neck dissection or with radiotherapy. The tonsil is one of the most common sites within the oropharynx, covered on our tonsil cancer page.

What to Expect

Before treatment. A scope examination, a biopsy with HPV testing, staging scans and a tumour board review. Dr. Vidhyadharan explains the diagnosis, the plan and the likely recovery.

Treatment. TORS, radiotherapy or a combination, with neck treatment as needed.

After treatment. Follow-up checks the throat and neck, with support for swallowing and speech during recovery.

Outcomes

The outlook for oropharyngeal cancer is generally good, and especially good for HPV-related cancers caught early, many of which are cured. Stage at diagnosis and complete treatment are the main factors. Function-sparing approaches like TORS help patients keep good swallowing and speech, so quality of life after treatment is usually high. A sore throat or neck lump that does not settle should be checked early, because the earlier the cancer is found, the gentler the treatment can be.

Why Choose Dr. Vidhyadharan at THANC Hospital

  • India's first TORS-assisted total laryngectomy (2022), a landmark in robotic head and neck surgery.
  • FICRS certification in robotic surgery, with fellowship training at Royal Adelaide Hospital, Australia.
  • MCh (Head & Neck Surgery) and European Board certification (FEB-ORL HNS).
  • 3000+ head and neck operations, the volume linked to better outcomes.
  • The da Vinci Xi robot and a full oncology team at THANC Hospital.

Treatment Cost and Insurance

The cost depends on the stage, the treatment (surgery, radiotherapy or both), and the length of stay. Most major health insurers in India cover cancer treatment, including cashless treatment at empanelled hospitals. Eligible patients may also use government schemes such as Ayushman Bharat (AB-PMJAY) or the Tamil Nadu CMCHIS.

THANC Hospital gives a clear, itemised estimate during your consultation. To see Dr. Vidhyadharan Sivakumar, request an appointment online.

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Frequently Asked Questions

Oropharyngeal cancer is cancer of the middle part of the throat, the oropharynx. This includes the tonsils, the base of the tongue, the soft palate and the back wall of the throat. Many of these cancers are now linked to HPV infection, as well as to tobacco and alcohol.

Common signs include a persistent sore throat, difficulty or pain when swallowing, a lump in the neck, ear pain on one side, a change in voice, and sometimes a feeling of something stuck in the throat. A lump in the neck is often the first sign of an HPV-related throat cancer.

Yes. A large and growing share of oropharyngeal cancers are caused by HPV infection. HPV-related cancers often affect slightly younger, non-smoking patients and usually respond very well to treatment, with a better outlook than tobacco-related cancers.

TORS, or Transoral Robotic Surgery, uses the da Vinci robot to remove throat tumours through the mouth, with no external cuts. It gives a magnified, precise view and is well suited to tonsil and tongue-base cancers. Benefits include no neck scar, good swallowing and speech outcomes, and faster recovery. Dr. Vidhyadharan performed India's first TORS-assisted total laryngectomy.

Treatment depends on the stage and whether it is HPV-related. Options include TORS robotic surgery, radiotherapy, and chemoradiation. Early cancers can often be treated with surgery or radiotherapy alone, while advanced cancers may need a combination. The neck is usually treated as well.

Diagnosis involves examination with a flexible scope, a biopsy, HPV testing, and scans (CT, MRI or PET-CT) to stage the cancer and check the neck. Every case is reviewed by a multidisciplinary tumour board.

The outlook is generally good, especially for HPV-related cancers caught early, which respond very well to treatment. Stage at diagnosis and complete treatment are the main factors. Early assessment of a persistent sore throat or neck lump gives the best results.

Dr. Vidhyadharan Sivakumar is a European Board-certified Head & Neck Surgical Oncologist at THANC Hospital, with an MCh in Head & Neck Surgery, FICRS certification in robotic surgery, and over 3000 head and neck operations.

Dr. Vidhyadharan Sivakumar

About the Author

Dr. Vidhyadharan Sivakumar

MCh (Head & Neck Surgery) · FEB-ORL HNS · FICRS

Head & Neck Surgical Oncologist & Laryngologist at THANC Hospital, Chennai. With 15+ years of experience and 3000+ complex surgeries, trained across 8 countries including fellowship at Royal Adelaide Hospital, Australia.

Head & Neck CancerRobotic SurgeryThyroid SurgeryVoice RestorationSkull Base SurgeryReconstruction

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